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Cholesterol Absorption Inhibitor. First line defense for those who cannot tolerate statins.
While Statins stop your liver from making cholesterol, Ezetimibe stops your gut from absorbing it. It is often the first line of defense for those who cannot tolerate statins due to muscle pain.
Taking 10mg Ezetimibe + 5mg Rosuvastatin is often far more effective (and has fewer side effects) than taking 40mg of Rosuvastatin alone.
10mg once daily
Any time of day, with or without food
Synergistic effect: Blocks both production and absorption
Mechanism: Inhibits NPC1L1 transporter in the intestine, preventing cholesterol absorption. Lowers LDL by 15-20%, ApoB by similar amount.