14.1 Telmisartan (The BP Standard)

Blood Pressure, PPAR-gamma & Visceral Fat. More than just a blood pressure medication.

Blood Pressure

PPAR-gamma

Visceral Fat

Longevity

More Than Just BP

Telmisartan is technically an ARB (Angiotensin Receptor Blocker) for blood pressure. But in the biohacking world, it is prized as a unique PPAR-gamma agonist. This means it helps reorganize fat storage away from visceral organs and improves insulin sensitivity.

🏆 Why It's The Favorite

Kidney Protection

Reduces intraglomerular pressure. Essential for longevity and kidney health. Protects against diabetic nephropathy.

Insulin Sensitivity

Works synergistically with Metformin (without the gut issues). PPAR-gamma activation improves glucose uptake.

24-Hour Half-Life

Only once-a-day dosing needed (unlike Losartan which requires twice daily). Better compliance and consistent coverage.

💊 Standard Protocol

Dosage:

20-80mg once daily (typically 40mg)

Timing:

Morning with or without food

Starting Dose:

Start with 20mg, titrate up if needed

Duration:

Long-term (lifelong for BP control)

Note: Monitor blood pressure 2 weeks after starting. Can take 2-4 weeks for full PPAR-gamma effects on insulin sensitivity.

🔗 Related Tools

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