10.2 Depression Protocols

Beyond SSRIs. Targeting neuroplasticity deficits to promote actual healing of the brain's emotional circuits.

Depression

Neuroplasticity

Semax

BPC-157

The Neuroplasticity Approach

SSRIs just flood the synapse. Peptides (Semax, BPC-157) target the root cause: Brain Derived Neurotrophic Factor (BDNF) and Dopamine Receptor density.
This promotes physical healing of the neural networks responsible for mood and motivation.

Anhedonic (No Pleasure)

"Nothing feels good anymore."

Target: Dopamine (Semax, BPC-157)

Melancholic (Classic)

"Persistent sadness, guilt."

Target: Serotonin/BDNF (Selank + Semax)

Anxious Depression

"Depressed AND restless."

Target: HPA Axis (Selank, DSIP)

Atypical (Leaden)

"Heavy limbs, oversleeping."

Target: Inflammation (BPC-157, Thymosin)

The Semax Reset

8-Week Protocol

Weeks 1-2 (Loading)Semax 300mcg 2x/day + Selank HS
Subtle clarity
Weeks 3-4 (Building)Add BPC-157 250mcg Daily
Motivation return
Weeks 5-8 (Consolidate)Reduce Semax to 1x/day
Stable mood

Focus on BPC-157

The Dopamine Reset

Not just for joints. BPC-157 upregulates Dopamine receptors and heals gut-brain inflammation. It is a powerful antidepressant, especially for anhedonia and post-stimulant recovery.

Protocol250-500mcg SubQ daily for 4-8 weeks.

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