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9.3 Kisspeptin-10: The Master Switch

Stimulating the reproductive axis upstream. The safe alternative to HCG.

Hormones

Testosterone

Fertility

GnRH

The Upstream Regulator.

Kisspeptin is the "master switch" of the HPG axis. It stimulates GnRH neurons to release LH/FSH. Unlike exogenous Testosterone (which shuts you down), Kisspeptin activates natural production.

🔬 The HPG Axis

1. KISSPEPTINHypothalamus → GnRH Neurons

2. Pituitary (LH / FSH)Signals the Gonads

3. Gonads (Testosterone + Sperm)Downstream Output

🎯 Kisspeptin vs. TRT

❌ Exogenous TRT

• Shuts down natural production
• Testicular Atrophy
• Fertility Impairment

✅ Kisspeptin

• Stimulates natural production
• Preserves testicular function
• Enhances Fertility

💉 Dosing Protocols

Goal	Dose	Frequency
Libido Boost	100-200mcg	As needed (1-2hr before)
TRT Support	100mcg	2x Daily
Fertility	50-100mcg	2-3x Daily (Pulsatile)
PCT	100mcg	2x Daily (4-6 weeks)

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