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Exercise in a Bottle. A mitochondrial-derived peptide that activates the AMPK pathway, mirroring the metabolic effects of exercise.
The "Fake Sprint." MOTS-c sends the signal that you just ran a marathon, forcing the body to burn sugar and fat rapidly to replenish energy stores (AMPK activation).
Use this interactive flowchart to identify your metabolic goal and get a personalized protocol recommendation.
Select your primary metabolic challenge and get a customized protocol
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Moves glucose from blood into muscle (GLUT4) to be burned, not stored.
Tells mitochondria to switch fuel sources to fat.
May prevent muscle breakdown while dieting.
Peter Attia's Zone 2 Training signals mitochondrial biogenesis. MOTS-c amplifies this signal.
No. It lacks mechanical tension for muscle growth. It generates the fuel signal, not the strength signal.
Yes. Both activate AMPK. Monitor blood sugar closely (Hypoglycemia risk).
Female, Age 38 - Active runner but stalled fat loss. Post-pregnancy weight plateaus.
Active runner but stalled fat loss despite consistent exercise
Exercise plateau reached
MOTS-c (5mg) 3x/week pre-run injection
Mitochondrial optimization protocol
Lost 8lbs visceral fat, 1 mile split dropped 30 seconds
Significant performance and body composition improvement
Sustained fat loss without muscle loss. Improved running endurance
Complete metabolic optimization achieved
Successfully broke through exercise plateau with mitochondrial peptide support, achieving targeted body recomposition
"Mitochondrial health is the foundation of cellular longevity. Peptides like SS-31 and MOTS-c represent a new generation of mitochondrial protectors that work at the cellular level."
Mitochondrial health and longevity
— FoundMyFitness