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TLDR: The "Second Brain."
70% of your immune system lives in your gut (GALT). If your gut lining is compromised ("Leaky Gut"), your immune system is in a constant state of panic. You cannot fix autoimmunity without fixing the gut first.
The Analogy: Your gut lining is the Castle Wall protecting your bloodstream from the barbarians (bacteria/food particles) in your stomach.
| Agent | Role | Dose |
|---|---|---|
| BPC-157 (Oral) | Structural Repair | 500mcg twice daily (AM/PM) |
| KPV (Oral/Spray) | Anti-Inflammatory | 200mcg daily |
| Larazotide (Advanced) | Tight Junction Zipper | 1mg with meals (if available) |
Use this interactive flowchart to quickly pick a starting protocol (then jump to the right chapter and tools).
Pick your primary gut issue and get a starting stack + next best action.
A: No. While injectable BPC is systemic, Oral BPC-157 (Arg-Salt) is superior for gut issues because it directly coats the site of injury (gastric mucosa) on the way down.
A: Spray is better for sinus/systemic issues (Mold). Capsules are better for lower GI issues (Crohn's/Colitis) as they reach the colon.
29yo Female, Moderate flare. Mayo Score 8/12. Failed mesalamine and budesonide.
Bowel movements reduced from 8/day to 4/day
50% reduction in frequency
Abdominal pain reduced by 80%
Significant pain relief
Colonoscopy showed significant mucosal healing
Structural improvement confirmed
Mayo Score 1/12 (clinical remission)
Complete remission achieved
Gastroenterologist's assessment: 'This peptide combination provided steroid-level efficacy without the side effects.'
If you have MCAS, starting BPC-157 can sometimes trigger a histamine flare. Start with a micro-dose (50mcg) to test tolerance. KPV is generally well tolerated as it stabilizes mast cells.