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The Post-Peptide Era: Gene therapy, CRISPR, and the dawn of self-editing biology.
Peptides are powerful, but they're still external signals. The future of biohacking involves reprogramming the body at the genetic level—making your cells produce their own therapeutic proteins permanently. We're entering the era of self-editing biology.
External signaling molecules, daily/weekly dosing, temporary effects.
Viral vectors delivering therapeutic genes, one-time treatments, FDA approvals expanding.
Precise gene editing for enhancement, not just disease, polygenic modifications.
Synthetic biology, designer organisms, full cellular reprogramming.
Adeno-Associated Virus delivers genes into cells. One-time treatment, permanent effect.
Precise gene editing. Cut, delete, or insert DNA sequences at specific locations.
Temporary gene expression without DNA changes. Cells produce proteins from mRNA template.
Change single DNA letters without cutting. Safer, more precise than CRISPR cuts.
While many of these technologies are currently reserved for treating rare genetic diseases, the rapid drop in cost and increasing precision means that optimization is the logical next step. Understanding these mechanisms is essential for the 2026+ biohacking landscape.
Next: Follistatin Deep Dive